This backfires spectacularly when the truly gigantic alien/Killer Croc hybrid runs loose, having no reservations about killing her. Batman: One crossover with Alien has the head of a weapons manufacturing company think it's a good idea to hybridize the xenomorphs with Batman's Rogues Gallery ( The Joker, Poison Ivy, etc.), with some kind of genetic manipulation so they won't attack her, and Take Over the World.(He was actually expecting Toguro to chicken out, since it was much bigger than him, which would've given Tarukane an excuse to pay Toguro less for his services.) Toguro says he'd rather not because he has a soft spot for animals, but he kills it easily. He asks Younger Toguro to demonstrate how tough he actually is by fighting it. In YuYu Hakusho, Corrupt Corporate Executive Tarukane breeds a giant beast intended for use by the military from several of Earth's top predators.Right after his birth Cloning Blues sets in, but Giovanni did manage to trick him for a while into serving as his attack animal. He was cloned from the DNA of the mythical and nigh-all-powerful Pokemon Mew by scientists for Giovanni, the boss of Team Rocket. For bonus points, the armor is a Restraining Bolt because they are too good a killbeast.

Neon Genesis Evangelion: This is the true nature of the Evas they're giant mutated versions of the monsters they try to kill, all wrapped up in armor to make them look like giant robots.

Boa vs python midget